{"id":10521,"date":"2024-09-17T11:44:55","date_gmt":"2024-09-17T08:44:55","guid":{"rendered":"https:\/\/uokerbala.edu.iq\/en\/?p=10521"},"modified":"2024-09-17T11:44:55","modified_gmt":"2024-09-17T08:44:55","slug":"university-of-kerbala-discussing-an-m-a-thesis-entitled-investigating-serum-levels-of-osteoporosis-and-inflammatory-anti-inflammatory-biomarkers-in-rheumatoid-arthritis-patients-with-or-withou","status":"publish","type":"post","link":"https:\/\/uokerbala.edu.iq\/en\/university-of-kerbala-discussing-an-m-a-thesis-entitled-investigating-serum-levels-of-osteoporosis-and-inflammatory-anti-inflammatory-biomarkers-in-rheumatoid-arthritis-patients-with-or-withou\/","title":{"rendered":"University of Kerbala Discussing an M.A Thesis entitled Investigating Serum Levels of Osteoporosis and inflammatory \/ anti-inflammatory Biomarkers in rheumatoid arthritis patients (with or without) type 2 diabetes before and after treatment with nano_ structural metformin”"},"content":{"rendered":"

College of Medicine \/ University of Kerbala has discussed the M.A thesis which is entitled Investigating Serum Levels of Osteoporosis and inflammatory \/ anti-inflammatory Biomarkers in rheumatoid arthritis patients (with or without) type 2 diabetes before and after treatment with nano_ structural metformin”, submitted by (Shadha Jassim Hatem Jassim).<\/span>
\nThe study aims at identifying inflammatory and anti-inflammatory biomarkers for early detection of rheumatoid arthritis (RA) and diagnosing to prevent development of type 2 diabetes (T2DM), and association between markers of variables related to the disease, and the use of metformin, a common drug for T2DM, is effectively delivered using hyaluronic acid- (HA) encapsulated nucleosomes, to prove potential of this approach in treatment of RA, using molecular PCR method for different factors, such as total oxidative stress state (TOS), interleukin (IL-23) and nuclear factor of activated TGF-\u03b2 (TGF-\u03b2). Cytoplasmic cells (1NFATC), and receptor activator of nuclear factor kappa-B ligand (RANKL) are evaluated in both Peripheral Blood Mononuclear Cells (PBMCs) before and after treatment. The study also highlights potential of HA-coated nanoparticles (Hyaluronic acid) as an effective drug delivery system for metformin, targeting rheumatoid arthritis and type 2 diabetes derived from PBMCs. The Hyalo-Nio-met NPs nanocomposite shows desirable properties, including stability and controlled drug release. The incorporation of HA enhances targeting and therapeutic effect of these niosomes.<\/span><\/p>\n

\"\"<\/p>\n

\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

College of Medicine \/ University of Kerbala has discussed the M.A thesis which is entitled Investigating Serum Levels of Osteoporosis and inflammatory \/ anti-inflammatory Biomarkers in rheumatoid arthritis patients (with or without) type 2 diabetes before and after treatment with nano_ structural metformin”, submitted by (Shadha Jassim Hatem Jassim). The study aims at identifying inflammatory […]<\/p>\n","protected":false},"author":42,"featured_media":10522,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ocean_post_layout":"","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"","ocean_second_sidebar":"","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"","ocean_custom_header_template":"","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"","ocean_menu_typo_font_family":"","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"","ocean_post_oembed":"","ocean_post_self_hosted_media":"","ocean_post_video_embed":"","ocean_link_format":"","ocean_link_format_target":"self","ocean_quote_format":"","ocean_quote_format_link":"post","ocean_gallery_link_images":"on","ocean_gallery_id":[],"footnotes":""},"categories":[59,53],"tags":[],"class_list":["post-10521","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-important-news","category-news","entry","has-media"],"jetpack_featured_media_url":"https:\/\/uokerbala.edu.iq\/en\/wp-content\/uploads\/sites\/7\/2024\/09\/photo_2024-09-17_01-35-38.jpg","_links":{"self":[{"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/posts\/10521","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/users\/42"}],"replies":[{"embeddable":true,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/comments?post=10521"}],"version-history":[{"count":1,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/posts\/10521\/revisions"}],"predecessor-version":[{"id":10524,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/posts\/10521\/revisions\/10524"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/media\/10522"}],"wp:attachment":[{"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/media?parent=10521"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/categories?post=10521"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/uokerbala.edu.iq\/en\/wp-json\/wp\/v2\/tags?post=10521"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}