تأثير جرع مختلفة من مبيد Bifenthrin على بعض معايير الدم الفسلجية والهرمونية والكيمو حيوية والجنينية في إناث الجرذ الأبيض اثناء الحمل

The effect of dirrent doses of Bifenthrin insecticide on some physiological , harmonic , biochemical and embryonic blood standards in the females of white rats during pregnancy .

SUMMARY

This study was conducted at the University of Karbala / College of Education for Pure Science / Life Sciences Division for the period from January 2012 until June 2013 . The study aims to determine the impact of pesticide bifenthrin in some standards functional and histological female rat white pregnant women during pregnancy as it used (176 ) animal laboratory used them (96) Female and ( 32) said of the Rat White was divided females to four transactions by (24) Female for each transaction , as was the dosage female mice pregnant women in the first treatment with distilled water starting from the sixth day of pregnancy until the eighteenth day of pregnancy , and the second treatment was Tgeraaha pesticide bifenthrin dose allowed (0.02) mg / kg of body weight starting from the sixth day of pregnancy until the eighteenth day of pregnancy and the third treatment was Tgeraaha pesticide bifenthrin dose above the allowed (0.03) mg / kg of body weight starting from the sixth day of pregnancy until the eighteenth day of pregnancy , the treatment fourth and final was Tgeraaha dose of pesticide bifenthrin twice the dose allowed (0.04) mg / kg of body weight starting from the sixth day of pregnancy until the eighteenth day of pregnancy and took clips histologic liver and kidneys for the purpose of study histologic changes , he also used a group of animals of ( 48) Female to determine the dose half -lethal (LD50) of the pesticide under study bifenthrin. The results showed the following: –
1 – half the dose lethal to search under study is 9 mg / kg of body weight, there was a big difference between the dose of the current search for previous studies .
2 – The results showed that the dosage pregnant females treated nets Bifenthrin dose allowed T2, and the dose above the permitted T3 and twice the dose allowed T4 led to a significant decrease P <0.05 in the rate of the number of red blood cells Red blood corpuscles (RBC) and the size of PCV (PCV Packed cell volume and concentration Alimoklopan Hemoglobin (Hb) and white blood cells Leucocytes Count and the preparation of platelets The numbers plalelet blood and hormonal Alostarugen Estrogen and progesterone progesterone compared with the control group .
3 – observed significant increase 0.05> P levels in the effectiveness of the functions of the liver enzymes Alanine transaminase (ALT), Aspartate transaminase (AST), Alkaline Phosphates (ALP) compared with the control group .
4 – occurrence of morphological changes in the organs of the body , compared with the control group consisted of those changes in the liver and lungs and Alkli of inflation in the chest area .
5 – bloody congestion and necrosis of liver cells and atrophy of the glomerulus in the tissue of the liver , and kidney compared with the control group .
We conclude that the insecticide Bifenthrin has a detrimental effect in patients Turkar allowed (0.02) mg / kg of body weight of the pesticide and the effect will be satisfactory to both the functional and histological criteria .