تأثير هرمونات الغدة الدرقية على الحوامل في محافظة كربلاء

The Impact of thyroid hormones in pregnant women in kerbala province

Abstract

This study was designed to investigate the relationship between thyroid hormones and pregnancy, as well as the prevalence and impact of thyroid dysfunction in pregnant women with risk factors for recurrent miscarriage, intrauterine growth restriction, hypertension and diabetes occurring during pregnancy. Serum of 115 pregnant women infected with risk factors distributed over different periods of pregnancy, and their ages ranged between 15-43 years, and the serum of 50 healthy pregnant women aged between 15-43 years was considered as a control group. This study was conducted in the Obstetrics and Gynecology Hospital in Karbala during the period (September) 1/9/2020 to (March) 1/3/2021. Thyroid hormones TSH, FT4, FT3 were measured using Mini Vedas.in the serum of pregnant women. The results of the study showed that there is a relationship between thyroid hormones and pregnancy, significant difference was found in TSH, FT4 and FT3 compared to the control group, Hypothyroidism led to an increase in TSH and a significant decrease in FT3 and FT4 hormones. FT4 compared to the control group by 75%, while the increase in thyroid hormones (hyperthyroidism) was a significant decrease in TSH and a significant increase in FT3 and FT4 compared to the control group by 40%. It also found a relationship between hypothyroidism and hyperthyroidism with risk factors, where the prevalence of recurrent miscarriage was 22%, hypertension 18%, diabetes mellitus 10%, and intrauterine growth restriction 25% in hypothyroidism, while the prevalence of recurrent miscarriage was in hyperthyroidism. 8%, high blood pressure 12%, diabetes 15%, intrauterine growth restriction 5%, the results of the study also showed the effect of repeated abortions on weight gain and obesity. It also found that the incidence of growth restriction factor was higher in the age group 15-24 years by 13.9%, and the rate of recurrent miscarriage 12.1% is the highest in the age group 25-34 years while hypertension was 13%. , which is highest in the 35-43 age group. So is the relationship between intrauterine growth restriction, recurrent miscarriage, diabetes, and hypertension.