دراسة بعض الجوانب الوبائية والمناعية للنساء المصابات بطفيلي المشعرات المهبلية Trichomonas vaginalis في محافظة كربلاء

Rp.SStudy of some epidemiological and immunological aspects of women infected with Trichomonas vaginalis in Karbala governorate pdf.

Summary
This study included an investigation of the extent of the prevalence of vaginal trichomoniasis among women attending the Obstetrics and Gynecology Teaching Hospital in Karbala Governorate and private women’s clinics for the period from the beginning of November 2020 to June 2021, as the number of samples examined was 350 samples, including 100 samples from infected women, whose ages ranged between 15-65 years old, and the infection rate among them was 28.57%. The highest infection rate was recorded in the age group 15-24 years, when the infection rate reached 34.28%. The lowest infection rate was for the age group 55-65, with a rate of 16.21%. 35.71% %. The infection rate according to the place of residence in rural women was 28.65% higher than that of urban women, and according to social status, married women formed a high infection rate of 29.82%, followed by divorced women and then widows, while unmarried women did not show an infection rate, and this study also dealt with knowing the infection rate among women Educated and uneducated women, as women with primary education had the highest infection rate, 29.33%. As for abortions, non-abortioned women recorded the highest infection rate, 34.09%.
This study also dealt with other factors, namely the use of contraceptives. Women who used contraceptives showed an infection rate of 25%, which is lower than that of women who did not use contraceptives by 28.83%. As for the distribution of infection with Trichomonas vaginalis according to fertility, sterile women had a higher infection rate than women. Non-sterile women were 35.71%, 27.95%, respectively.
The results of the current study revealed an increase in the level of IgA – IgM – IgG antibodies in the sera of female Trichomonas vaginalis parasites, which amounted to (0.070 + 0.11), (0.09 + 0.16), (0.071 + 0.13), respectively, compared to the control group (14.32 + 6.76), respectively. (1.92 + 1.04, (2.004 + 1.12) with a statistically significant difference at the probability level of 0.05%.
The results of examining the concentration of cytokines LTB-4, TGF-β, MCP-1, IL-10, NO, using the ELISA technique showed an increase in their concentration in the serum of Trichomonas vaginalis (4.38 ± 1.13) (35.65 + 41.3 (97.93 + 28.6) (97.93 + 28.6) (96.41 + 25.9) pg / ml, respectively, compared to the control group (4.37 ± 1.07)) (15.83 ± 3.1) (22.06 ± 10.74) (19.14 ± 7.14) (0.203 ± 0.22 pg / ml), respectively, as this increase recorded a difference Statistically significant at a probability level of less than %5..