University of Kerbala
College of Pharmacy / University of Kerbala has discussed the M.A thesis which is entitled discussed Effect of Genetic polymorphisms of CYP3A4 and ABCB1 on Tamoxifen Efficacy used in treatment of Iraqi Breast Cancer Women”.
The study, submitted by Arjwan Fouad Hussein, aims at Investigating multiple genetic forms among Iraqi women with breast cancer and the effect of these genetic variants on effectiveness of Tamoxifen.
The study shows a significant effect of genetic polymorphisms in genes targeted by the study on response to treatment with Tamoxifen, indicating the importance of genetic evaluation to improve effectiveness of treatment and reduce side effects.
The study recommends conducting genetic tests to identify genetic polymorphisms before starting treatment and using the results obtained to determine a therapeutic roadmap that can be employed in order to obtain maximum efficiency of treatment used while ensuring the lowest incidence of side effects and enhancing awareness among doctors to integrate these tests into treatment strategies.
