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University of Kerbala Investigates an M.A Thesis entitled Activity of some plant extracts and antibiotics against Pseudomonas aeruginosa and Candida albicans

 

Being submitted by Taif Ridha Saleh_ Department of Biology, College of Science _ University of Kerbala has discussed the M.A thesis which is examined the effect of a group of antibiotics and plant extracts on certain types of resistant bacteria and fungi that cause infections, particularly those isolated from various clinical samples.
The study focuses on testing effectiveness of natural extracts, mixed or alone, such as ginger, garlic, coriander, and marjoram. It also investigates their effectiveness when combined with certain antibiotics and observed their ineffectiveness against these organisms due to acquired resistance.

The thesis also finds out that some extracts exhibited varying inhibitory effects. The ginger and garlic mixture is the most prominent in terms of efficacy and acceptable odor, while remaining formulations failed to achieve effective synergy when combined with ginger.
The study recommends the need to expand molecular research to understand mechanism of action of these compounds, study their toxicity to human cells, evaluate their ability to affect cell membranes, and measure their resistance to virulence factors associated with these organisms.