دراسة كيموحياتية للعلاقة بين بعض العناصر الأثرية وهرمونات الغدة الدرقية لدى المرضى المصابين باضطراب الغدة الدرقية.

Biochemical study of the association between Zn, Cu, and Se with hormones of thyroid gland in patients with thyroid disorder.

This study was conducted in AL-Hussein General Hospital and out patients clinic in Karbala city ,to determine the value of thyroid  hormone (T3 triiodothyronine, T4 tetraiodothyrionine and thyroid stimulating hormone and the concentration of the Zinc, Copper and Selenium in patients with thyroid disorder (hyperthyroidism 31) and hypothyroidism21), and evaluate the association between them. All patients were (females) the range of is age from 23to 57 years, and Control Groups Were 40,They were collected from the medical staff and patients relatives who were free from signs and symptoms of thyroid disorder all of these group are females .

The study shows the following results:-

1- The concentration of serum Zinc in patient with hyperthyroidism was higher than control (p<0.001).

 2- The concentration of serum Copper in patient with hyperthyroidism was higher than control (p<0.001).

3- The concentration of serum Selenium in patient with hyperthyroidism was lower than control (p<0.001).

4- The concentration of serum Zinc in patient with hypothyroidism was lower than control (p<0.001).

5- The concentration of serum Copper in patient with hypothyroidism was lower than control (p<0.001).

6- The concentration of serum Selenium in patient with hypothyroidism was lower than control (p<0.001).

7- Determination of serum Copper concentration in atomic absorption and with spectrophtometric method, and then compared.

8- The result of atomic absorption method more economic, more precise and easier than spectrophtometric method.